The US dispatched a small number of special forces troops to northern Syria to assist Kurdish Pershmerga and support Syrian rebel groups seeking to overthrow Mr Assad. Yet last Thursday, two Syrian Su-24 ground-attack planes targeted an area close to where they are based.
The incident in the northern Syrian city of Hasakah, highlighted the complicated and perilous situation in Syria, where the US and Russia are on different sides of a civil war that has now raged for five years and killed or displaced millions of people. While in disagreement over Mr Assad, the two countries are seeking to cooperate in efforts to attack and destroy Isis bases in Syria.
Lieutenant General Stephen Townsend, who took control of US forces in Syria and Iraq last week, said he had voiced his concerns – passing a message to Syria through Russian intermediaries.
“We’ve informed the Russians where we’re at … [they] tell us they’ve informed the Syrians, and I’d just say that we will defend ourselves if we feel threatened,” Mr Townsend told CNN.